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Bacteria Induce Prolonged PMN Survival via a Phosphatidylcholine-Specific Phospholipase C- and Protein Kinase C-Dependent Mechanism

Polymorphonuclear leukocytes (PMNs) are essential for the human innate immune defense, limiting expansion of invading microorganisms. PMN turnover is controlled by apoptosis, but the regulating signaling pathways remain elusive, largely due to inherent differences between mice and humans that underm...

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Detalhes bibliográficos
Main Authors: Erttmann, Saskia F., Gekara, Nelson O., Fällman, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3909253/
https://ncbi.nlm.nih.gov/pubmed/24498214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087859
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