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Formulation and Optimization of Nonionic Surfactants Emulsified Nimesulide-Loaded PLGA-Based Nanoparticles by Design of Experiments

This investigation aimed to develop nimesulide (NMS)-loaded poly(lactic-co-glycolic acid) (PLGA)-based nanoparticulate formulations as a biodegradable polymeric drug carrier to treat rheumatoid arthritis. Polymeric nanoparticles (NPs) were prepared with two different nonionic surfactants, vitamin E...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Turk, Ceyda Tuba Sengel, Oz, Umut Can, Serim, Tugrul Mert, Hascicek, Canan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Springer US 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3909165/
https://ncbi.nlm.nih.gov/pubmed/24222270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-013-0048-9
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