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Ethylcellulose-Based Matrix-Type Microspheres: Influence of Plasticizer RATIO as Pore-Forming Agent

In this study, ethylcellulose (EC)-based microsphere formulations were prepared without and with triethyl citrate (TEC) content of 10% and 30% by water-in-oil emulsion-solvent evaporation technique. Diltiazem hydrochloride (DH) was chosen as a hydrophilic model drug and used at different drug/polyme...

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Библиографические подробности
Главные авторы: Sengel-Turk, C. Tuba, Hascicek, Canan, Gonul, Nursin
Формат: Artigo
Язык:Inglês
Опубликовано: Springer US 2011
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225517/
https://ncbi.nlm.nih.gov/pubmed/21887603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-011-9680-4
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