Astrocyte-Derived Proinflammatory Cytokines Induce Hypomyelination in the Periventricular White Matter in the Hypoxic Neonatal Brain

Hypoxic exposure in the perinatal period causes periventricular white matter damage (PWMD), a condition associated with myelination abnormalities. Under hypoxic conditions, glial cells were activated and released a large number of inflammatory mediators in the PWM in neonatal brain, which may result...

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Autors principals: Deng, Yiyu, Xie, Di, Fang, Ming, Zhu, Gaofeng, Chen, Chunbo, Zeng, Hongke, Lu, Jia, Charanjit, Kaur
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3909103/
https://ncbi.nlm.nih.gov/pubmed/24498101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087420
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