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Inhibition of sodium-linked glucose reabsorption normalizes diabetes-induced glomerular hyperfiltration in conscious adenosine A(1)-receptor deficient mice

AIM: Glomerular hyperfiltration is commonly observed in diabetics early after the onset of the disease and predicts the progression of nephropathy. Sustained hyperglycemia is also closely associated with kidney hypertrophy and increased electrolyte and glucose reabsorption in the proximal tubule. In...

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Hlavní autoři: Sällström, Johan, Eriksson, Terese, Fredholm, Bertil B., Persson, A. Erik G., Palm, Fredrik
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3909021/
https://ncbi.nlm.nih.gov/pubmed/23901799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/apha.12152
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