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A kinetic approach to the sequence–aggregation relationship in disease-related protein assembly

It is generally accepted that oligomers of aggregating proteins play an important role in the onset of neurodegenerative diseases. While in silico aggregation studies of full length amyloidogenic proteins are computationally expensive, the assembly of short protein fragments derived from these prote...

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Detalhes bibliográficos
Main Authors: Barz, Bogdan, Wales, David J., Strodel, Birgit
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3908877/
https://ncbi.nlm.nih.gov/pubmed/24401100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp412648u
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