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Endothelin-Converting Enzyme-1 (ECE-1) Is Post-Transcriptionally Regulated by Alternative Polyadenylation

Endothelin-converting enzyme-1 (ECE-1) is the enzyme predominantly responsible for producing active endothelin-1 (ET-1), a mitogenic peptide implicated in the aetiology of a number of diseases, including cancer. Elevated levels of ECE-1 have been observed in a range of malignancies, with high expres...

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Detalhes bibliográficos
Main Authors: Whyteside, Alison R., Turner, Anthony J., Lambert, Daniel W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3908869/
https://ncbi.nlm.nih.gov/pubmed/24497914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083260
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