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Stabilization of the long central helix of troponin C by intrahelical salt bridges between charged amino acid side chains.

The unusual dumbbell shape of troponin C is due to the presence of a long alpha-helix of nine turns that connects the amino- and carboxyl-terminal calcium-binding domains. The center of the long helix appears to be stabilized by several salt bridges. The long helix is also bent about 16 degrees at g...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphovsmän: Sundaralingam, M, Drendel, W, Greaser, M
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 1985
Ämnen:
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390886/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3865207/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.23.7944
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