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The adaptor protein SLP-76 regulates HIV-1 release and cell to cell transmission in T-cells

HIV-1 infection in T-cells is regulated by T-cell receptor (TCR) activation. However, the cellular proteins of the TCR pathway that regulate HIV-1 infection are poorly characterized. Here, we elucidated the role of SLP-76, a key adaptor protein of the TCR signaling complex, in HIV-1 infection. We ob...

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Autori principali: Nagaraja, Tirumuru, Anand, Appakkudal R., Zhao, Helong, Ganju, Ramesh K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3908818/
https://ncbi.nlm.nih.gov/pubmed/22323535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102106
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