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An antipeptide antibody that specifically inhibits insulin receptor autophosphorylation and protein kinase activity.

Two site-specific antibodies that immunoprecipitate the human insulin receptor have been prepared by immunizing rabbits with chemically synthesized peptides derived from the cDNA-predicted amino acid sequence of the beta subunit of the proreceptor. Antibodies to the carboxyl terminus (AbP5) and to a...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Herrera, R, Petruzzelli, L, Thomas, N, Bramson, H N, Kaiser, E T, Rosen, O M
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1985
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390877/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2415975/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.23.7899
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