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Insulin activates a tyrosine-specific protein kinase in extracts of 3T3-L1 adipocytes and human placenta.

Insulin activates a tyrosine-specific cAMP-independent protein kinase when added directly to detergent extracts of differentiated 3T3-L1 adipocytes and humal placental membranes. The kinase is also activated by antibody to the insulin receptor and, to a lesser extent, by proinsulin. It catalyzes the...

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Bibliographic Details
Main Authors: Petruzzelli, L M, Ganguly, S, Smith, C J, Cobb, M H, Rubin, C S, Rosen, O M
Format: Artigo
Language:Inglês
Published: 1982
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC347219/
https://ncbi.nlm.nih.gov/pubmed/6294652
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