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Lysine residue 121 in the proposed ATP-binding site of the v-mos protein is required for transformation.

The transforming gene product encoded by Moloney murine sarcoma virus clone 124, p37mos, contains a lysine residue (lysine-121) that is conserved among all members of the protein kinase family. This lysine has been shown to be part of a conserved ATP-binding site in both the catalytic subunit of the...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Hannink, M, Donoghue, D J
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 1985
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390876/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2999782/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.23.7894
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