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An effective and effecient peptide binding prediction approach for a broad set of HLA-DR molecules based on ordered weighted averaging of binding pocket profiles

BACKGROUND: The immune system must detect a wide variety of microbial pathogens, such as viruses, bacteria, fungi and parasitic worms, to protect the host against disease. Antigenic peptides displayed by MHC II (class II Major Histocompatibility Complex) molecules is a pivotal process to activate CD...

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Autors principals: Shen, Wen-Jun, Zhang, Shaohong, Wong, Hau-San
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3908610/
https://ncbi.nlm.nih.gov/pubmed/24565049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-5956-11-S1-S15
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