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Biophysical characterization of α-synuclein and its controversial structure

α-synuclein, a presynaptic protein of poorly defined function, constitutes the main component of Parkinson disease-associated Lewy bodies. Extensive biophysical investigations have provided evidence that isolated α-synuclein is an intrinsically disordered protein (IDP) in vitro. Subsequently serving...

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Detalhes bibliográficos
Main Authors: Alderson, T Reid, Markley, John L
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3908606/
https://ncbi.nlm.nih.gov/pubmed/24634806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/idp.26255
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