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A critical role for IGF-II in memory consolidation and enhancement
We report that, in the rat, administering insulin-like growth factor II (IGF-II) significantly enhances memory retention and prevents forgetting. Inhibitory avoidance learning leads to an increase in hippocampal expression of IGF-II, which requires the transcription factor CCAAT enhancer binding pro...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3908455/ https://ncbi.nlm.nih.gov/pubmed/21270887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09667 |
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