A critical role for IGF-II in memory consolidation and enhancement

We report that, in the rat, administering insulin-like growth factor II (IGF-II) significantly enhances memory retention and prevents forgetting. Inhibitory avoidance learning leads to an increase in hippocampal expression of IGF-II, which requires the transcription factor CCAAT enhancer binding pro...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Chen, Dillon Y., Stern, Sarah A., Garcia-Osta, Ana, Saunier-Rebori, Bernadette, Pollonini, Gabriella, Bambah-Mukku, Dhananjay, Blitzer, Robert D., Alberini, Cristina M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3908455/
https://ncbi.nlm.nih.gov/pubmed/21270887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09667
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados