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Characterization of a Reduced Form of Plasma Plasminogen as the Precursor for Angiostatin Formation
Plasma plasminogen is the precursor of the tumor angiogenesis inhibitor, angiostatin. Generation of angiostatin in blood involves activation of plasminogen to the serine protease plasmin and facilitated cleavage of two disulfide bonds and up to three peptide bonds in the kringle 5 domain of the prot...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3908430/ https://ncbi.nlm.nih.gov/pubmed/24338014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.539924 |
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