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Increased Ribozyme Activity in Crowded Solutions
Noncoding RNAs must function in the crowded environment of the cell. Previous small-angle x-ray scattering experiments showed that molecular crowders stabilize the structure of the Azoarcus group I ribozyme, allowing the ribozyme to fold at low physiological Mg(2+) concentrations. Here, we used an R...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3908428/ https://ncbi.nlm.nih.gov/pubmed/24337582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.527861 |
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