NF-κB and Enhancer-binding CREB Protein Scaffolded by CREB-binding Protein (CBP)/p300 Proteins Regulate CD59 Protein Expression to Protect Cells from Complement Attack

The complement system can be activated spontaneously for immune surveillance or induced to clear invading pathogens, in which the membrane attack complex (MAC, C5b-9) plays a critical role. CD59 is the sole membrane complement regulatory protein (mCRP) that restricts MAC assembly. CD59, therefore, p...

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Hlavní autoři: Du, Yiqun, Teng, Xiaoyan, Wang, Na, Zhang, Xin, Chen, Jianfeng, Ding, Peipei, Qiao, Qian, Wang, Qingkai, Zhang, Long, Yang, Chaoqun, Yang, Zhangmin, Chu, Yiwei, Du, Xiang, Zhou, Xuhui, Hu, Weiguo
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
Témata:
Gene Regulation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3908404/
https://ncbi.nlm.nih.gov/pubmed/24338025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.525501
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