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Role of Intrinsic Protein Disorder in the Function and Interactions of the Transcriptional Coactivators CREB-binding Protein (CBP) and p300

The transcriptional coactivators CREB-binding protein (CBP) and p300 undergo a particularly rich set of interactions with disordered and partly ordered partners, as a part of their ubiquitous role in facilitating transcription of genes. CBP and p300 contain a number of small structured domains that...

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Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Dyson, H. Jane, Wright, Peter E.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807259/
https://ncbi.nlm.nih.gov/pubmed/26851278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R115.692020
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