Limited proteolysis of the bifunctional thymidylate synthase-dihydrofolate reductase from Leishmania tropica.

The structure and activity of the bifunctional thymidylate synthase-dihydrofolate reductase (TS-DHFR) from the protozoan parasite Leishmania tropica were examined by limited proteolysis with five different endopeptidases. Each reaction resulted in a rapid, time-dependent loss of TS activity and no e...

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Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Garvey, E P, Santi, D V
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 1985
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390814/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3903747/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.21.7188
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