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Limited proteolysis of the bifunctional thymidylate synthase-dihydrofolate reductase from Leishmania tropica.

The structure and activity of the bifunctional thymidylate synthase-dihydrofolate reductase (TS-DHFR) from the protozoan parasite Leishmania tropica were examined by limited proteolysis with five different endopeptidases. Each reaction resulted in a rapid, time-dependent loss of TS activity and no e...

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Dettagli Bibliografici
Autori principali: Garvey, E P, Santi, D V
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1985
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC390814/
https://ncbi.nlm.nih.gov/pubmed/3903747
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