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Limited proteolysis of the bifunctional thymidylate synthase-dihydrofolate reductase from Leishmania tropica.

The structure and activity of the bifunctional thymidylate synthase-dihydrofolate reductase (TS-DHFR) from the protozoan parasite Leishmania tropica were examined by limited proteolysis with five different endopeptidases. Each reaction resulted in a rapid, time-dependent loss of TS activity and no e...

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Bibliografski detalji
Glavni autori: Garvey, E P, Santi, D V
Format: Artigo
Jezik:Inglês
Izdano: 1985
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC390814/
https://ncbi.nlm.nih.gov/pubmed/3903747
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