Binding of a possible transition state analogue to the active site of carboxypeptidase A.
The mode of binding of the competitive inhibitor 2-benzyl-3-formylpropanoic acid to the active site of carboxypeptidase A has been studied by x-ray diffraction methods to a resolution of 1.7 A. The actual species bound to the enzyme was determined to be the gem-diol resulting from covalent hydration...
Na minha lista:
| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1985
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390783/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3863130/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.20.6840 |
| Tags: |
Sem tags, seja o primeiro a adicionar uma tag!
|