A novel function for Myc: inhibition of C/EBP-dependent gene activation.
We have investigated the effect of the v-Myc oncoprotein on gene expression in myelomonocytic cells. We find that v-Myc dramatically down-regulates the expression of myelomonocytic-specific genes, such as the chicken mim-1 and lysozyme genes, both of which are known targets for C/EBP transcription f...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1996
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39078/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8692870/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.13.6635 |
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