A novel function for Myc: inhibition of C/EBP-dependent gene activation.

We have investigated the effect of the v-Myc oncoprotein on gene expression in myelomonocytic cells. We find that v-Myc dramatically down-regulates the expression of myelomonocytic-specific genes, such as the chicken mim-1 and lysozyme genes, both of which are known targets for C/EBP transcription f...

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Detalles Bibliográficos
Autores principales: Mink, S, Mutschler, B, Weiskirchen, R, Bister, K, Klempnauer, K H
Formato: Artigo
Lenguaje:Inglês
Publicado: 1996
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC39078/
https://ncbi.nlm.nih.gov/pubmed/8692870
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