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A novel function for Myc: inhibition of C/EBP-dependent gene activation.

We have investigated the effect of the v-Myc oncoprotein on gene expression in myelomonocytic cells. We find that v-Myc dramatically down-regulates the expression of myelomonocytic-specific genes, such as the chicken mim-1 and lysozyme genes, both of which are known targets for C/EBP transcription f...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Mink, S, Mutschler, B, Weiskirchen, R, Bister, K, Klempnauer, K H
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39078/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8692870/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.13.6635
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