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Osteogenic lineage restriction by osteoprogenitors cultured on nanometric grooved surfaces: The role of focal adhesion maturation()

The differentiation of progenitor cells is dependent on more than biochemical signalling. Topographical cues in natural bone extracellular matrix guide cellular differentiation through the formation of focal adhesions, contact guidance, cytoskeletal rearrangement and ultimately gene expression. Oste...

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Detalhes bibliográficos
Main Authors: Cassidy, John W., Roberts, Jemma N., Smith, Carol-Anne, Robertson, Mary, White, Kate, Biggs, Manus J., Oreffo, Richard O.C., Dalby, Matthew J.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907683/
https://ncbi.nlm.nih.gov/pubmed/24252447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2013.11.008
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