Osteogenic lineage restriction by osteoprogenitors cultured on nanometric grooved surfaces: The role of focal adhesion maturation()

The differentiation of progenitor cells is dependent on more than biochemical signalling. Topographical cues in natural bone extracellular matrix guide cellular differentiation through the formation of focal adhesions, contact guidance, cytoskeletal rearrangement and ultimately gene expression. Oste...

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Bibliographic Details
Main Authors: Cassidy, John W., Roberts, Jemma N., Smith, Carol-Anne, Robertson, Mary, White, Kate, Biggs, Manus J., Oreffo, Richard O.C., Dalby, Matthew J.
Format: Artigo
Language:Inglês
Published: Elsevier 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907683/
https://ncbi.nlm.nih.gov/pubmed/24252447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2013.11.008
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