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Chloroquine Stimulates Cl(−) Secretion by Ca(2+) Activated Cl(−) Channels in Rat Ileum

Chloroquine (CQ), a bitter tasting drug widely used in treatment of malaria, is associated gastrointestinal side effects including nausea or diarrhea. In the present study, we investigated the effect of CQ on electrolyte transport in rat ileum using the Ussing chamber technique. The results showed t...

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Detalhes bibliográficos
Main Authors: Yang, Ning, Lei, Zhen, Li, Xiaoyu, Zhao, Junhan, Liu, Tianjian, Ning, Nannan, Xiao, Ailin, Xu, Linlin, Li, Jingxin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907514/
https://ncbi.nlm.nih.gov/pubmed/24498157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087627
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