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Chloroquine Stimulates Cl(−) Secretion by Ca(2+) Activated Cl(−) Channels in Rat Ileum

Chloroquine (CQ), a bitter tasting drug widely used in treatment of malaria, is associated gastrointestinal side effects including nausea or diarrhea. In the present study, we investigated the effect of CQ on electrolyte transport in rat ileum using the Ussing chamber technique. The results showed t...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Yang, Ning, Lei, Zhen, Li, Xiaoyu, Zhao, Junhan, Liu, Tianjian, Ning, Nannan, Xiao, Ailin, Xu, Linlin, Li, Jingxin
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907514/
https://ncbi.nlm.nih.gov/pubmed/24498157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087627
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