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Chromatin context and ncRNA highlight targets of MeCP2 in brain

The discovery that Rett syndrome (RTT) is caused by mutation of the methyl-CpG-binding-protein MeCP2 provided a major breakthrough in understanding the neurodevelopmental disorder and accelerated MeCP2 research. However, gene regulation by MeCP2 is complicated. The current consensus for MeCP2 remain...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Maxwell, Scott S, Pelka, Gregory J, Tam, Patrick PL, El-Osta, Assam
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907483/
https://ncbi.nlm.nih.gov/pubmed/24270455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.26921
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