Mycophenolate Mofetil Enhances the Negative Effects of Sirolimus and Tacrolimus on Rat Kidney Cell Metabolism

BACKGROUND AND PURPOSE: Mycophenolate mofetil (MMF) per se is not known to have negative effects on the kidney. MMF alone or in combination with sirolimus, can be the basis of calcineurin inhibitor (CNI)-free, kidney sparing drug protocols. However, long-term outcomes in patients on MMF/SRL seem to...

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Main Authors: Klawitter, Jelena, Klawitter, Jost, Schmitz, Volker, Shokati, Touraj, Epshtein, Ekaterina, Thurman, Joshua M., Christians, Uwe
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907404/
https://ncbi.nlm.nih.gov/pubmed/24497939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086202
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