Investigation of Acetylcholine Receptor Diversity in a Nematode Parasite Leads to Characterization of Tribendimidine- and Derquantel-Sensitive nAChRs

Nicotinic acetylcholine receptors (nAChRs) of parasitic nematodes are required for body movement and are targets of important “classical” anthelmintics like levamisole and pyrantel, as well as “novel” anthelmintics like tribendimidine and derquantel. Four biophysical subtypes of nAChR have been obse...

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Bibliografiske detaljer
Main Authors: Buxton, Samuel K., Charvet, Claude L., Neveu, Cedric, Cabaret, Jacques, Cortet, Jacques, Peineau, Nicolas, Abongwa, Melanie, Courtot, Elise, Robertson, Alan P., Martin, Richard J.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907359/
https://ncbi.nlm.nih.gov/pubmed/24497826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003870
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