A Chaperone-Assisted Degradation Pathway Targets Kinetochore Proteins to Ensure Genome Stability

Cells are regularly exposed to stress conditions that may lead to protein misfolding. To cope with this challenge, molecular chaperones selectively target structurally perturbed proteins for degradation via the ubiquitin-proteasome pathway. In mammals the co-chaperone BAG-1 plays an important role i...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Kriegenburg, Franziska, Jakopec, Visnja, Poulsen, Esben G., Nielsen, Sofie Vincents, Roguev, Assen, Krogan, Nevan, Gordon, Colin, Fleig, Ursula, Hartmann-Petersen, Rasmus
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907333/
https://ncbi.nlm.nih.gov/pubmed/24497846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004140
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados