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Binding of protein kinase C to neutrophil membranes in the presence of Ca2+ and its activation by a Ca2+-requiring proteinase.

In the presence of micromolar concentrations of Ca2+, both protein kinase C and a cytosolic Ca2+-requiring neutral proteinase of human neutrophils become associated with the neutrophil membrane. Binding to the membrane results in activation of the proteinase, which then catalyzes limited proteolysis...

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Main Authors: Melloni, E, Pontremoli, S, Michetti, M, Sacco, O, Sparatore, B, Salamino, F, Horecker, B L
格式: Artigo
語言:Inglês
出版: 1985
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC390731/
https://ncbi.nlm.nih.gov/pubmed/2995965
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