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Large Inverted Duplications in the Human Genome Form via a Fold-Back Mechanism
Inverted duplications are a common type of copy number variation (CNV) in germline and somatic genomes. Large duplications that include many genes can lead to both neurodevelopmental phenotypes in children and gene amplifications in tumors. There are several models for inverted duplication formation...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3907307/ https://ncbi.nlm.nih.gov/pubmed/24497845 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004139 |
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