Large inverted duplications in amplified DNA of mammalian cells form hairpins in vitro upon DNA extraction but not in vivo.
I have analysed the duplex-to-hairpin transition of large inverted duplications with a short asymmetric center which are found in the amplified DNA of two mammalian cell lines resistant to cytotoxic drugs. Psoralen crosslinking experiments establish that this transition does not occur in vivo, but t...
Guardat en:
| Publicat a: | Nucleic Acids Res |
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| Autor principal: | |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
1989
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| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC335197/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2602136/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/17.23.9557 |
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