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Automated Discovery of Tissue-Targeting Enhancers and Transcription Factors from Binding Motif and Gene Function Data

Identifying enhancers regulating gene expression remains an important and challenging task. While recent sequencing-based methods provide epigenomic characteristics that correlate well with enhancer activity, it remains onerous to comprehensively identify all enhancers across development. Here we in...

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Detalhes bibliográficos
Main Authors: Tuteja, Geetu, Moreira, Karen Betancourt, Chung, Tisha, Chen, Jenny, Wenger, Aaron M., Bejerano, Gill
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907286/
https://ncbi.nlm.nih.gov/pubmed/24499934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003449
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