Integrated genomic analysis identifies recurrent mutations and evolution patterns driving the initiation and progression of follicular lymphoma

Follicular lymphoma (FL) is an incurable malignancy(1), with transformation to an aggressive subtype being a critical event during disease progression. Here we performed whole genome or exome sequencing on 10 FL-transformed FL pairs, followed by deep sequencing of 28 genes in an extension cohort and...

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Autori principali: Okosun, Jessica, Bödör, Csaba, Wang, Jun, Araf, Shamzah, Yang, Cheng-Yuan, Pan, Chenyi, Boller, Sören, Cittaro, Davide, Bozek, Monika, Iqbal, Sameena, Matthews, Janet, Wrench, David, Marzec, Jacek, Tawana, Kiran, Popov, Nikolay, O’Riain, Ciaran, O’Shea, Derville, Carlotti, Emanuela, Davies, Andrew, Lawrie, Charles H., Matolcsy, Andras, Calaminici, Maria, Norton, Andrew, Byers, Richard J., Mein, Charles, Stupka, Elia, Lister, T. Andrew, Lenz, Georg, Montoto, Silvia, Gribben, John G., Fan, Yuhong, Grosschedl, Rudolf, Chelala, Claude, Fitzgibbon, Jude
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907271/
https://ncbi.nlm.nih.gov/pubmed/24362818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2856
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