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Ligand Mobility Regulates B Cell Receptor Clustering and Signaling Activation
Antigen binding to the B cell receptor (BCR) induces receptor clustering, cell spreading, and the formation of signaling microclusters, triggering B cell activation. Although the biochemical pathways governing early B cell signaling have been well studied, the role of the physical properties of anti...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Biophysical Society
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3907214/ https://ncbi.nlm.nih.gov/pubmed/24411234 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.10.043 |
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