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Ligand Mobility Regulates B Cell Receptor Clustering and Signaling Activation

Antigen binding to the B cell receptor (BCR) induces receptor clustering, cell spreading, and the formation of signaling microclusters, triggering B cell activation. Although the biochemical pathways governing early B cell signaling have been well studied, the role of the physical properties of anti...

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Autors principals: Ketchum, Christina, Miller, Heather, Song, Wenxia, Upadhyaya, Arpita
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907214/
https://ncbi.nlm.nih.gov/pubmed/24411234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.10.043
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