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DNA Methylation is Associated with an Increased Level of Conservation at Nondegenerate Nucleotides in Mammals
DNA methylation at CpG dinucleotides can significantly increase the rate of cytosine-to-thymine mutations and the level of sequence divergence. Although the correlations between DNA methylation and genomic sequence evolution have been widely studied, an unaddressed yet fundamental question is how DN...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2014
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| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3907051/ https://ncbi.nlm.nih.gov/pubmed/24157417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/mst208 |
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