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DNA Methylation is Associated with an Increased Level of Conservation at Nondegenerate Nucleotides in Mammals

DNA methylation at CpG dinucleotides can significantly increase the rate of cytosine-to-thymine mutations and the level of sequence divergence. Although the correlations between DNA methylation and genomic sequence evolution have been widely studied, an unaddressed yet fundamental question is how DN...

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Autori principali: Chuang, Trees-Juen, Chen, Feng-Chi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907051/
https://ncbi.nlm.nih.gov/pubmed/24157417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/mst208
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