Prostaglandin F(2α) FP receptor antagonist improves outcomes after experimental traumatic brain injury

BACKGROUND: Injuries to the brain promote upregulation of prostaglandins, notably the proinflammatory PGF(2α), and overactivation of their cognate G-protein-coupled FP receptor, which could exacerbate neuronal damage. Our study is focused on investigation of the FP receptor as a target for novel neu...

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Main Authors: Glushakov, Alexander V, Robbins, Sean W, Bracy, Connor L, Narumiya, Shuh, Doré, Sylvain
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2013
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907016/
https://ncbi.nlm.nih.gov/pubmed/24172576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-10-132
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