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Latent myostatin has significant activity and this activity is controlled more efficiently by WFIKKN1 than by WFIKKN2

Myostatin, a negative regulator of skeletal muscle growth, is produced from myostatin precursor by multiple steps of proteolytic processing. After cleavage by a furin-type protease, the propeptide and growth factor domains remain associated, forming a noncovalent complex, the latent myostatin comple...

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Autori principali: Szláma, György, Trexler, Mária, Patthy, László
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley & Sons Ltd 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3906830/
https://ncbi.nlm.nih.gov/pubmed/23829672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.12377
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