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Genetic analysis of the role of proteolysis in the activation of latent myostatin.

Myostatin is a secreted protein that normally acts to limit skeletal muscle growth. As a result, there is considerable interest in developing agents capable of blocking myostatin activity, as such agents could have widespread applications for the treatment of muscle degenerative and wasting conditio...

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Autore principale: Se-Jin Lee
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2008-02-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC2237902?pdf=render
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