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Separation of the transcriptional coactivator and antirepression functions of transcription factor IIA.

Human transcription factor IIA (TFIIA) is composed of three subunits (alpha, beta, and gamma). TFIIA interacts with the TATA-box binding protein and can overcome repression of transcription. TFIIA was found to be necessary for VP16-mediated transcriptional activation through a coactivator function....

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Principais autores: MA, D, Olave, I, Merino, A, Reinberg, D
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 1996
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39068/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8692860/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.13.6583
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