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The allo- and viral-specific immunosuppressive effect of belatacept, but not tacrolimus, attenuates with progressive T cell maturation
Tacrolimus impairs allo- and viral-specific T cell responses. Belatacept, a costimulation-based alterative to tacrolimus, has emerged with a paradoxical picture of less complete control of alloimmunity with concomitant impaired viral immunity limited to viral-naïve patients. To reconcile these signa...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3906634/ https://ncbi.nlm.nih.gov/pubmed/24472192 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.12574 |
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