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Loss of pigment epithelium-derived factor: a novel mechanism for the development of endocrine resistance in breast cancer

INTRODUCTION: Despite the benefits of endocrine therapies such as tamoxifen and aromatase inhibitors in treating estrogen receptor (ER) alpha-positive breast cancer, many tumors eventually become resistant. The molecular mechanisms governing resistance remain largely unknown. Pigment epithelium-deri...

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Main Authors: Jan, Rifat, Huang, Min, Lewis-Wambi, Joan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3906603/
https://ncbi.nlm.nih.gov/pubmed/23151593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3356
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