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Mapping the AAV Capsid Host Antibody Response toward the Development of Second Generation Gene Delivery Vectors

The recombinant adeno-associated virus (rAAV) gene delivery system is entering a crucial and exciting phase with the promise of more than 20 years of intense research now realized in a number of successful human clinical trials. However, as a natural host to AAV infection, anti-AAV antibodies are pr...

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Autores principales: Tseng, Yu-Shan, Agbandje-McKenna, Mavis
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3906578/
https://ncbi.nlm.nih.gov/pubmed/24523720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00009
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