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Microbials for the production of monoclonal antibodies and antibody fragments
Monoclonal antibodies (mAbs) and antibody fragments represent the most important biopharmaceutical products today. Because full length antibodies are glycosylated, mammalian cells, which allow human-like N-glycosylation, are currently used for their production. However, mammalian cells have several...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Elsevier Science Publishers
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3906537/ https://ncbi.nlm.nih.gov/pubmed/24183828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibtech.2013.10.002 |
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