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Microbials for the production of monoclonal antibodies and antibody fragments

Monoclonal antibodies (mAbs) and antibody fragments represent the most important biopharmaceutical products today. Because full length antibodies are glycosylated, mammalian cells, which allow human-like N-glycosylation, are currently used for their production. However, mammalian cells have several...

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Detalhes bibliográficos
Main Authors: Spadiut, Oliver, Capone, Simona, Krainer, Florian, Glieder, Anton, Herwig, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science Publishers 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3906537/
https://ncbi.nlm.nih.gov/pubmed/24183828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibtech.2013.10.002
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