Different functions of HOPS isoforms in the cell: HOPS shuttling isoform is determined by RIP cleavage system

Hepatocyte odd protein shuttling (HOPS) moves between nucleus and cytoplasm. HOPS overexpression leads to cell cycle arrest in G(0)/G(1), and HOPS knockdown causes centrosome alterations, with subsequent abnormal cell division. Recently, we demonstrated that HOPS acts as a functional bridge in NPM-p...

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Main Authors: Castelli, Marilena, Piobbico, Danilo, Bartoli, Daniela, Pieroni, Stefania, Brunacci, Cinzia, Bellet, Marina Maria, Chiacchiaretta, Martina, Della Fazia, Maria Agnese, Servillo, Giuseppe
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3906245/
https://ncbi.nlm.nih.gov/pubmed/24240191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.27054
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